Despite the current advances in the treatment for prostate cancer, the patients often develop resistance to the conventional therapeutic interventions.Therapy-induced drug resistance and tumor progression have been associated with cellular plasticity acquired due to reprogramming at the molecular and phenotypic levels.The plasticity of the tumor ce
Abstract Physics informed neural network (PINN) demonstrates powerful capabilities in solving forward and inverse problems of nonlinear partial differential equations (NLPDEs) through combining data-driven and physical constraints.In this paper, two PINN methods that CEREBRUM CEREBOOST WITH DHA adopt tanh and sine as activation functions, respectiv
Cellular protein homeostasis Cargo Net is tightly regulated by ubiquitination.Responsible for target protein ubiquitination is a class of enzymes, the so-called ubiquitin (Ub) E3-ligases.They are opposed to a second class of enzymes, called DeUBiquitinating enzymes (DUBs), which can remove polyubiquitin chains from their specific target proteins.Th
This paper addresses the robust control for a slung-mass quadrotor under DRESSER abrupt velocity changes.The proposed algorithm is based on a sliding mode controller applied to the quadrotor translational dynamics considering the slung-mass angle as feedback.A Lyapunov candidate function is used to demonstrate system stability.Numerical simulations
Abstract Background: Whole-genome sequencing (WGS) has traditionally been used in infection prevention to confirm or refute the presence of an outbreak after it has occurred.Due to decreasing costs of WGS, an increasing number of institutions have been utilizing WGS-based surveillance.Additionally, machine learning or statistical modeling to supple